Sunday 23 September 2012

Watch Torchwood Season 4 Episode 8 - Entertainment


Watch Torchwood Season 4 Episode 8OH DEAR!!! Watch Torchwood Season 4 Episode 8 this Friday with "End of the Road", while the society is on the verge of falling apart, Rex is forced to take drastic measures. Meanwhile, someone thought to be dead comes back to confront Jack. Join us and watch Torchwood Season 4 Episode 8 online here:

WATCH IT HERE

Torchwood is a British science fiction television programme created by Russell T Davies. The series is a spin-off from Davies' 2005 revival of the long-running science fiction programme Doctor Who. As a show, Torchwood has transitioned its broadcast channel every year since its inception, moving from BBC Three to BBC Two to BBC One, and acquiring US financing in its fourth series. In contrast to Doctor Who, whose target audience includes adults as well as children, Torchwood is aimed at an older audience.

Previously on TorchwoodEpisode 1 "Miracle Day"the world's population is gifted with immortality, the human race is doomed to become non-viable within four months as Earth's resources run out. CIA agent Rex Matheson discovers a secret conspiracy for the "miracle" event, and the clues lead him to the old Torchwood institute in Britain.

Episode 2 "Rendition"After the team are reunited, Jack ends up realising that he is now the most vulnerable person on the planet. A trip to America by plane ends up turning into a desperate battle to stay alive.

Episode 3 "Dead of Night"When the Torchwood team takes their chance to run, they are soon confronted with a new adversary that leads Jack to the mysterious Oswald Danes.

Episode 4 "Escape to LA"The Torchwood team follows PhiCorp to California to continue the fight, but walk straight towards a trap. Elsewhere, Oswald and Jilly face their own adversary.Episode 5 "Categories of Life"While their enemy draws closer, Torchwood solves the mystery of the "Miracle Day" and uncovers the horrible truth.Episode 6 "The Middle Men"Jack is left on his own when the rest of the team ends up trapped on different continents. However, time is running out and leaving him no choice than to go straight to the heart of the conspiracy.

Episode 7 "Immortal Sins"to keep her family safe, Gwen is forced to follow and uncover the Miracle's long history.

Torchwood follows the exploits of a small team of alien-hunters, who make up the Cardiff, Wales branch of the fictional Torchwood Institute, which deals mainly with incidents involving extraterrestrials. Its central character is Captain Jack Harkness (John Barrowman), an immortal ex-con man from the distant future who has lived on Earth since the 19th century; Jack originally appeared in the 2005 series of Doctor Who. Under Jack's leadership, the formerly morally ambivalent organisation operates under a much more humanist ethos. Other than Barrowman, the series' initial main cast consisted of Eve Myles, Burn Gorman, Naoko Mori and Gareth David-Lloyd. Their characters are each specialists for the Torchwood team, often tracking down aliens and defending the planet from alien and nefarious human threats. In its first two series, the show uses a time rift in Cardiff as its primary plot generator, accounting for the unusual preponderance of alien beings in Cardiff. Gorman and M ori's characters were written out of the programme after the second series. Recurring actor Kai Owen was promoted to the main cast in series three, in which David-Lloyd too was written out. Subsequently, American actors Mehki Phifer, Bill Pullman and Alexa Havins join the cast of the show for its fourth series.

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Eric Gozlan?s ?Beautiful Boy? - News


"Beautiful Boy" a production of Gold Rush Entertainment is set for release in June 2011. The movie is produced by, the president and CEO of Goldrush Entertainment Inc, Eric Gozlan. The movie has already achieved recognition by winning the the International Film Critics prestigious Prize at the 2010 Toronto International Film Festival. It was premiered on September 12, 2010 at the 35th Toronto International Film Festival in Toronto, Canada. It was also the official selection at the Tokyo International Film Festival and San Sebastian International Film Festival. The movie is written and directed by Shawn Ku. He is an extremely talented director. He has also won the Grand Jury Prize - Special Mention at AFI Fest for Samara (2001) for amazing performance by an actor. He also won the Special Jury Award at the Florida Film Festival in 2004 for inspired musical filmmaking for Pretty Dead Girl (2004). He recently won the 2010 International Critics' Award at the Toronto Internation al Film Festival in the discovery category for Beautiful Boy (2010). The movie contains power-packed performances by the brilliant Michael Sheen and Maria Bello. They both are extremely talented and vivacious actors. Their performances in the movie have once again proved their flair. Michael Sheen is an extremely experienced actor and has won several awards at the Kansas City film Awards, Los Angeles Film Critics Association Awards, Toronto Film Association Awards and Evening Standard British Film Awards. Maria Bello has also won many awards such as the Screen Actors Guild Award, the Blockbuster Entertainment Award, the Satellite Award, and more at the Central Ohio Film Critics Association Awards,Chicago Film Critics Association Awards, Kansas City Film Critics Circle Awards,New York Film Critics Circle Awards, the Online Film Critics Society Award and the Dixie Film Festival Awards. Michael Sheen and Maria Bello lived the characters of a troubled couple who are going throu gh a rough patch in their marriage. They are at the verge of getting a divorce and decide to give their marriage one more chance by planning a family vacation. It is then that their life is shattered by the news. Their 18-year old son was responsible for carrying out a mass shootout at his college followed by him taking his own life. The movie showcases the grief of the devastated parents. They try to question what went wrong in their child's upbringing that made their son take such a brutal step. It shows the pain they endure after the incident. It is an emotional story that holds the attention of the audience right up until the very last scene.

You can get more information about Eric Gozlan by visiting Film Investment



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Friday 21 September 2012

Democracy Watch, 2011 - Issue 13 - Society - Politics


Entrepreneurs on the roads and teachers on the streets, the government faces mass protest as well as allegations of apathy towards corruption. The Prosecutor General's Office bringing charges against former president Kuchma added some excitement to the political arena of Ukraine.

Continuing protests of entrepreneurs become "AutoMaidan"

The professed Ukrainian East-West divide was undermined recently as entrepreneurs from around the country united in protest against the latest batch of tax legislation brought about by the current government. Automobiles from Lviv, Lugansk, Mariupol and other cities from the eastern and western regions came to Kyiv to create a new form of protest already referred to as "AutoMaidan". The automobile protest lasted from the 21st till the 25th of March and ended with a rally at Kyivs European Square and presentation of demands to the government under the slogan "Take Ukraine away from the oligarchs and return it to its citizens". The event gathered over 500 entrepreneurs and a number of deputies from the opposition.

The protesters demanded the protection of the Constitution, called for an end to economic repression and social experiments under the mask of reform and requested favourable conditions for the development of business and the national economy. The participants of the motor rally also demanded that the government accept the legislative initiatives of the Entrepreneurs Council of Ukraine in the area of small and medium-sized business, which have been introduced for consideration in parliament. Over 200 organisations and trade unions participated in the discussion stage of these initiatives. Considering this delicate issue, Prime-Minister Azarov encharged the ministers of finance, justice, labour and social policy with the task of reviewing the aforementioned legislative initiatives. The Cabinet of Ministers has also criticised the repression of entrepreneurship and the massive shutdown of small and medium-sized businesses by their owners. In the case that protesters' demands remain unheard, and the new Tax Code remains unchanged from the version introduced on April 1, the country may face a new wave of protests.

People First Comment:

There is no limit to human ingenuity. No matter how many laws, or how many police or how much repression this government or the Rada choose to employ, free people will always find a way round it. It is a democratic right to be able to protest and the more governments do to prevent the public from exercising that right, the more creative they will be. This approach is novel as it does not defy the governments new rules on assembly as the people are simply sitting in their own cars and, as far as we know, there is no law against that... yet.

Ukraine is still losing the battle against corruption

Despite the adoption of new legislation, international organisations and the Ukrainian opposition share the opinion that the Ukrainian government is avoiding the real battle against corruption. Experts from the anticorruption organisation Transparency International also expressed concerns in conjunction with the law on public purchases. It is believed that Ukraine loses up to 3 billion Euros in budget funds each year due to inefficient tenders and is suggested that the Chairman of the Verkhovna Rada, Volodymyr Lytvyn, adapt the law in order to make information on tenders available to the public. Parliament approved the draft law "On the prevention of corruption in Ukraine" in the first reading but left a number of controversial provisions of the law to the second reading. This gave the opposition an opportunity to accuse the governing coalition of faking the fight against corruption. According to Arseniy Yatsenyuk, leader of the "Front Zmin" political party, the majority o f amendments offered by the opposition were rejected.

In the corruption perception index compiled by Transparency International in 2010, Ukraine ranked 134th of 180 nations. GRECO (Group of States against corruption) reported that Ukraine has not taken sufficient measures to combat corruption. EBRD representatives also noted that a high level of corruption does not allow Ukraine to implement structural changes in the agricultural sector.

People First Comment:

Corruption in Ukraine is no longer an abuse of the system it is the system. Corruption has become so endemic that the majority now expect to have to pay some petty bureaucrat something to get anything done. As a result nothing at all gets done and the nation simply grinds along at a snails pace. The new law designed to prevent corruption is farcical as it has been purposefully engineered by the Rada to catch everybody except those who have direct access to the State budget. The most telling example being the removal in the second reading of the clause that would require the families of public officials to make the same income declarations as the official as this would mean that they could not use their wives, children, brothers, sisters and probably their dog as surrogate owners whilst they plead honesty.

The only real way to rid the country of this curse is to follow the Georgian example where the President and all of his inner cabinet agree that corruption is socially, morally, ethically and financially unacceptable. Over the past 10 years the Georgian government has fired almost a million civil servants who had their fingers in the cash till. They tried to rehire around 30% but found that most had not changed from their old ways. Instead they hired young people, paid them properly and engineered a government policy of transparency through the highly visible provision of public services. It has been a spectacular success to the extent that the people now see the Militia as a force for public good where even the family fights and feuds for which Georgia was once famous are now resolved through the law. If Georgia can achieve this, so can Ukraine. Its only a matter of political will.

Charges against former president Leonid Kuchma affect Ukrainian politics

The Prosecutor General's Office has reopened a criminal investigation into former president Leonid Kuchma. He is accused of involvement in the Gongadze murder case. The ongoing criminal investigation involves the re-interrogation of all the witnesses including major Melnichenko who made scandalous records of conversations in the ex-president's office. From a legal perspective, even if Kuchma is found guilty of abusive exercise of power he will not suffer criminal punishment due to the expiry of the period of limitation - over 10 years have passed since the case was first opened. Therefore consequences are limited to reputational.

The reasons why the authorities reopened the Gongadze case with accusations against Kuchma remain unclear. They may need a powerful news item to distract society from the increased interest in social problems or perhaps they are attempting try to restructure Ukrainian politics or pressure the former president's son-in-law Viktor Pinchuk. Another explanation is that the Party of Regions is haunting Leonid Kuchma for his indecision during Orange events in 2004. Legal experts note that if Melnichenko's recordings are admissible in court for this case then such evidence may be used against other politicians who appear on the recordings. The reopening of the Gongadze case may be evidence of an attempt to influence various Ukrainian politicians including the Chairman of Verkhovna Rada Volodymyr Lytvyn and Prime-Minister Mykola Azarov. By filing a charge against the former president of Ukraine and pushing the case through the courts the authorities may prove their desire to be se en as possessing respect for justice and the democratic principle of transparency.

People First Comment:

Whatever decisions the government, court, or elite come to the people will not believe either the validity of the accusations or the decisions of the court. This is nothing more than smokescreen designed to give the impression that the administration is clamping down on abuse. Wisely the Old Fox has hired possibly the finest legal council money can buy in order to give the State prosecutors a run for their money however Ukrainian justice being what it is today this case will most likely join the 129,000 other Ukrainian cases waiting to be heard at the European Court of Human Rights.

Whilst we would all agree that those accused of crimes should face their day in court, we should also agree that in democratic society you are innocent until proven guilty beyond reasonable doubt. Clearly President Kuchma has been already tried in the court of public opinion as a result of the hysteria surrounding the authenticity of the Melnichenko tapes. But this does not mean that he is actually guilty. That is for the courts to decide based upon proven fact.

What is sad for public confidence and the whole Ukrainian justice system is that President Yushchenko did not pursue the case as soon as he came to office. Today, irrespective of the decision of the courts, justice will not be seen to have been done especially as the case is now outside the statute of limitation. If this is nothing more than a show trial then President Yanukovich had better plan to be in office for the foreseeable future as what is good for one former President can also apply to others.

Teachers' protest at Ukraines commitment to education

After a long period of relative tranquillity education workers launched campaign of protest against violations of their rights. Late January saw protests in front of the Cabinet of Ministers building, which gathered around 10 thousand members from education trade unions demanding a salary increase. There have been similar protests by teachers in Donetsk, Dnipropetrovsk, Zaporizhia, Lviv (which gathered over 5 thousand of protesters), and other cities of Ukraine. In total the protest movement has attracted over 20 thousand teachers from all over Ukraine.

Prime-Minister Mykola Azarov pulled Dmytro Tabachnyk, Minister of Education, Youth and Sports of Ukraine, up for allowing teachers to protest. He stated that the protests are indicative of the irresponsible work of the Minister and the local education administrations that finance education establishments. Azarov reproached Tabachnyk for not engaging the protesters in dialogue. The protests have resulted in a 20% salary increase for all education workers but only from the 1st of September 2011. According to the Minister of Finance of Ukraine Fedir Yaroshenko the government is prepared to allocate a further 420-430 million UAH providing a salary increase for around 350 thousand education workers. Before the teachers' protests there was the students' campaign in many Ukrainian cities that helped to prevent the implementation of changes to high educational establishments, which could have led to higher education fees and a smaller volume of government scholarships.

People First Comment:

There is a point in social dynamics known as the tipping point. It is that point in time where a group will finally say enough is enough and rebel. What is interesting about tipping points is that they cannot be predicted and sometimes cannot be controlled. When 20,000 people come out onto the streets a blind politician might well choose to ignore them as they do not seem to be too much of a threat but in reality this is often an indicator of more dangerous civil unrest boiling just under the surface.

If the government decides to award teachers a pay increase of 20% what about the doctors, nurses and social workers? Are they too not horribly underpaid? Then what about the miners, steel workers and government administrators should they not also be given a 20% pay rise? If the government indulge in selective pacification of one sector of public employees then all the other sectors will have every reason to feel that they too can protest and even go on strike. The net result is that by putting out one fire the government may well reach a tipping point where the rest of society rebels.

Tampering with the education system has made Mr Tabachnyk one of the most unpopular Ministers in the current government. Favouring the teachers over all the other public sectors can only add more fuel to the fire. But when it comes down to fellow party members perhaps, a severe public rebuke is the only punishment Prime Minister Azarov was allowed to administer.

Quote of the week:

People often say that, in a democracy, decisions are made by a majority of the people. Of course, that is not true. Decisions are made by a majority of those who make themselves heard and who vote a very different thing.

Walter H. Judd American politician and statesman

People First Foundation1 Skovorody Street, Kyiv 04070, UkraineTelephone: +38044 536 1508 / Fax +38044 536 1509



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Thursday 20 September 2012

Market Big or Die Extremely fast - Business


2009, Microsoft pulled the promotion on its Kin phones only 48 days when they went on sales.

In recent times, technology companies have happen to be cutting their losses with the help of increasing speed. Google proudly released Wave, its program of collaborative work gear, for the general community in May 2010. The application canceled Wave 77 a short time later. Palm announced the country's first tablet, all the Foleo, on May 30, 2007. By simply Sept. 4, the manufacturer halted development additionally, the product was never advertised.

Absolute Digital, maker for the Flip camcorder, had planned to secrete the Flip-Live on May 13, nonetheless Cisco, which previously had acquired Pure Digital last season, near the entire splitting on April 12.As of late, big technology companies - particularly those with the hypercompetitive smartphone and gadget industries - is commencing to resemble Hollywood film broadcasters. Just about every release needs will probably be blockbuster, as well as only measure of success is the opening-weekend gross. There may be little to no room for your sleeper indie reach that builds good testimonials to become a thorough performer with time.

Anytime Microsoft released the Wii in 2005, insurance carrier widespread reliability issues along with the console faced serious competition within the Nintendo Wii, yet the organization stayed the program, and now the Xbox is among the best-selling video game consoles in recent history. That sort of tenacity is very much in diminishing provide.Some analysts trace the origin of this blockbuster-or-bust mindset to Apple. Each release on the company's popular iPads not to mention iPhones crosses over into being a mainstream media situation. 's Hilwa, an analyst around the research firm IDC, referred to the accelerated lifecycle about high-end hardware while "Darwinian. "

"There's a straight of desperation coming from anyone whose name just isn't Apple, " proclaimed Mr. Hilwa.This crush of technological bloggers and Twitter-using premature adopters who chronicle just of news - bad and good - about new handsets and tablets also raises the stakes around just how well new products perform that you can purchase."You know pretty immediately, and in a highly public way, whether an item is successful or not likely, " talked about Mr. Hilwa.

Akin to opening week at the movies, fast reviews on online panning a fresh tablet or phone could be disastrous for its machines.

"Once you lose traction, it is hard to gain back it, " said Bob Jones, an analyst for Canalys.

The particular rapid life menstrual cycles of products can play together with the affections of people, who may rush out to become the first on the block with a new product, only to uncover that the manufacturer has canceled any future help or development several weeks after it made sale.Neal LoCurto, the master of TeamLogic IT, an i . t . consulting company throughout Syosset, D. Y., said he bought his TouchPad the morning it proceeded sale. "On launching day I visited Best Buy which will morning and waited along at the door, " Mr. LoCurto talked about. "I was the earliest one in as well as first one out there. "

Mr. LoCurto, what person ultimately grew unhappy with the TouchPad due to the lack of blog, got a refund for their TouchPad, yet he says he not even trusts H. K. "I sense you are they lied to all of us, " Mr. LoCurto claimed. "They didn't give it the possibility. "

Companies kill new products and solutions more quickly now due to its higher cost of keeping competitive, believed Jim McGregor, explore director for In-Stat, a market research firm. Fast pulling the plug on an obvious failure makes good sense, is usually can come to be embarrassing."The life cycles have grown short because there is obviously huge competition, " Mr. McGregor says. "Even need to make sure contain a blockbuster, you are aware of you're travelling to get leapfrogged in half a year. You have to turn up with something that knocks off of the pants and then follow it up. You can't basically sit there and assert, 'Hey, I've got profitable. ' "

In the truth of the TouchPad, analysts agree it been unsuccessful because its computer, webOS, had few in the apps that made Apple's ipad 3gs a runaway click, he said. Microsoft's Kin had the same problem.

Mr. McGregor mentioned that Google TV, Google's Internet-connected television accessory, washed out into obscurity as a result of content providers declined to produce their content available. Google had prearranged various manufacturers as partners, for example LG, Toshiba not to mention Sharp, just to tell many of them last December to be able to delay the release on their Google TV products. While Google's strategy for Google TV remains unknown, none of partners have come out with a The search engines TV product."The content may be valued at more than the machine, " says Mr. McGregor. "If a person don't have everything - prefer to, the particular applications and the knowledge - you might drop your anchorman and jump from the ship. "Perhaps even mighty Apple hasn't been always so skilled. Like others today, Apple company company suffered a streak of misfortune with new products regarding green decade ago along with, for example them, it cut their losses. The manufacture r killed the power Mac G4 Cube, a computing, for 2001 after merely 11 months since consumers believed the value was too superior and balked at requiring you to buy a monitor on their own.A pair of days after announcing it is kill the TouchPad, L. DELAWARE. started unloading its inventory via a fire sale. This steep discount - 80 percent up from the original price - succeeded in setting off a buying frenzy this H. P. 's executives wanted when they introduced it.

THEY WOULD. P. 's retailer, together with Best Order, Goal and Wal-Mart, quickly ran out of TouchPads after putting them on discount sales for $100 for your 16G version and $150 for those 32G version. When originally in July, they were detailed at $500 together with $600.

People strategized on over the internet message boards about how to get a TouchPad. H. W. 's call center has been overwhelmed.

"All this clamoring with the TouchPad, kind of bittersweet, " H. V. 's customer provider arm said in a post on Twittollower.

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American Bathroom Hidden Camera,Spy Hidden Camera - Technology


Tokyo's pricey bars and pubs can quickly bust a wallet -- and sometimes a marriage.Although it's hardly the experience of the typical tourist to Japan, most surely can't help but wonder about the apparent conformity on show among the legions of black-suited office workers crowding every train and coffee shop in central Tokyo.

Are they really all just drones in service to the Greater Good and are they actually as boring as they seem? In short, the answer to both is a definite "No" -- something I found out when I donned a black suit of my own and joined the salaryman army.

The first thing that would really strike anyone experiencing the daily life of a typical Tokyo white-collar worker for the first time would be the staunch patience and discipline needed to survive in the Japanese business world.

From the start of each day, you utterly surrender your individuality, first physically on the jam-packed commuter trains, then mentality at an office dominated by groupthink and tedious rules. Day after day you walk the line, kowtow to superiors and swallow your opinions.

It's in this repressed atmosphere that I've witnessed the flourishing practice of hesokuri, or keeping a secret pocket money stash, which works as a kind of freedom fund for salarymen. The inspiration? Restoring personal sanity with off-family-balance-sheet detours into Tokyo's retail wonderland.

"Almost all Japanese salarymen have a secret bank account," says Mr. H., an executive at my former employer, one of Japan's largest conglomerates.

"There are so many ways to use it, and it actually is basic policy for Japanese companies to support it."

Recessionary shift

Hmm -- hang out here, or head home to the wife and her spreadsheets?Hesokuri is a term that's been around since the Edo period of Japanese history. It's often been equated with money that housewives secretly stash away for shopping and dining.

But that definition was more applicable to the economic bubble period of the late 1970s and 1980s, when huge corporate expense accounts paid for the salaryman's hedonistic entertainment and housewives raided their husbands' fat company bonuses.

More on CNNGO: The salaryman strikes back

From what I've seen, two decades of stagnation have drastically altered the use of hesokuri. The stakes these days are much lower -- big expense accounts are gone and fat bonuses are rare, so the modern wife has slim pickings.

So now, it's the salarymen who quietly and methodically create a hesokuri with skimmed wads of cash.

Hats in the airIn the places I've worked, hesokuri has been a natural expression of accumulated, unexpressed employee frustration.

When work is finally over, the tension is explosively released -- never belligerently, but rather with an earnest feeling shared with co-workers, like hats being thrown in the air together. I wish I could find a bar in the United States half as cheery as the typical Tokyo izakaya.

For many salarymen -- especially those with no time to see family or friends -- this hesokuri-funded, nightly drinking bout is the one thing that makes weekday life worth living. And in lieu of the long-gone corporate expense account, the spirit-building value this represents to the typical company cannot be understated.

A hush-hush topicStill, you won't find "hesokuri" listed in any Japanese company's handbook. In the beginning, I had to quietly ask around to learn more, starting with a veteran manager who sat next to me.

His response was instructive. He leaned over in his chair and whispered conspiratorially: "If hesokuri yes ..." He made a motion of upending a bottle and sucked noisily. "If hesokuri no ..." He made a choking sound and pretended to slash his lower stomach with a sword in the manner of seppuku, the samurai ritual suicide by disembowelment.

He then pointed over to the desk of Mr. H, my boss, indicating he'd hook me up if I wanted: "Get hesokuri ... you very like."

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Monday 17 September 2012

WWE WrestleMania 28 Live Stream - Watch 720p HD Stream Online - News - World News


PPV) event, produced annually in late March or early April by , a professional wrestling promotion based in Connecticut. first producedW R E S T L E - Z O N E . N E Tthe event in 1985 to be its premiere annual event and has since produced twenty-seven editions with the twenty-eighth and twenty-ninth scheduled to take place in Miami Gardens, Florida in 2012 and East Rutherford, New Jersey in 2013.[1][2] regards it as a flagship event due to it being the most successful and longest-running professional wrestling event in history. WrestleMania was conceptualized by owner Vince McMahon.WrestleMania's widespread success helped transform the professional wrestling industry and make the most successful wrestling promotion in the world.[citation needed] The event has facilitated the rise to stardom of wrestlers including The Undertaker, Hulk Hogan, Bret Hart, Shawn Michaels, Steve Austin, Triple H, The Rock, John Cena, and Batista. Celebrities such as Aretha Franklin, Cyndi Lauper , Muhammad Ali, Mr. T, Alice Cooper, Lawrence Taylor, Pamela Anderson, Mike Tyson, Donald Trump, Floyd Mayweather, Snoop Dogg and others have participated or made special appearances within the events.WrestleMania propels the worldwide commercial success of the through media, merchandise and shows. All of the events produced have been sold out within a short period of time, with recent editions being sold out within minutes of tickets going on sale. The first WrestleMania was held in Madison Square Garden in New York City; the 10th and 20th editions were also held there. WrestleMania III in Detroit was the highest-attended indoor sports event in the world, with 93,173 fans in attendance. The record stood until February 14, 2010, when the 2010 NBA All-Star Game broke the indoor sporting event record with an attendance of 108,713 at Cowboys Stadium.[3] All but the two editions held in Toronto, Canada have been hosted in U.S. cities.WrestleMania 28 may feature a handful of main event-caliber matches, but the only logical match to close the show is John Cena vs. The Rock.This feud has been a dream come true for many fans.It is a feud that, despite what many may say, features two of the best performers to ever grace theDespite my belief that a World championship match should always close out a pay-per-view event (except for Royal Rumble, of course), history has shown us that it is imperative for a match of this magnitude to main event WrestleMania.However, the biggest match of the card was a similar Generation vs. Generation dream match between The Rock and Hulk Hogan, which saw arguably the most iconic crowd reaction in history, when the Toronto fans created a double turn and turned The Rock heel and Hogan face.When it came time for the epic encounter between Triple H and Jericho, the crowd was dead.They had exerted so much energy during Rocky vs. Hogan that they couldn't give it their all for the championship match. Despite putting on a great perf ormance and completing his comeback, Triple H wasn't given a fair shake--neither was Jericho--and the match was seen as a letdown.The fact of the matter is that Cena vs. The Rock is bigger than the championship. It is the match we're paying to see above the rest and the match for which we want to give our all. It is the match that has the ability to transcend all others and go down as one of the most important and greatest matches in professional wrestling history.It doesn't matter what anybody says. It doesn't matter how many times we want to second-guess ourselves. Cena vs. The Rock is the main event and must finish the show.wrestle-zone.net

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Sunday 16 September 2012

Natural Killer Cells Breakthrough Treatment For Stage 4 Breast Cancer and Stage 4 Cancer - Health - Cancer


=> Immunotherapy Escalates War on stage 4 Breast Cancer and stage 4 cancer

The field of cancer immunology is, to date, more than 30 years old, and has advanced rapidly, with definitive speed over the last 10 years. Immunotherapy, the use of the stimulated immune system to effectively battle disease, has clustered into various subsets including immune system growth factors, monoclonal antibodies, cellular therapies, and, in some cases, combinations of two or more of these strategies. Recent advances in adoptive immunotherapy (focused on the expansion of specific disease-fighting white blood cells and their infusion into patients) have led to profound discoveries that will undoubtedly impact the treatment of stage 4 breast cancer and other stage 4 cancer over the expanse of the next ten years.

=> Traditional Breast Cancer Protocols Come Up Far Too Short

Breast cancer treatment in the early stages has, for an extensive period of time, been mostly confined to lumpectomy, combined with radio and chemotherapy to increase survival. With late stage or stage 4 breast cancer we typically witness a similar focus, however, it is not uncommon to see additional forms of radiotherapy and chemotherapy treatments if the patient had grown refractory to the initial regimen.

Immunotherapy provides an innovative way of targeting metastasis and pinpointing the primary site all at one time. Data clearly shows that as tumors and cancer stages progress so do immune blocking mechanisms deemed(up regulated) by cancers to self-protect. By depleting such negative factors and integrating a specialized cancer vaccine that employs the body's own natural killer cells - Envita has instituted a powerful and ambitious method designed to tackle stage 4 breast cancer and other stage 4 cancer.

=> Stage 4 Breast Cancer and other stage 4 cancer Immunotherapy has a Clear Leader: Envita

Multitudes of published studies have demonstrated the effects of adoptive immune therapy in cancer patients. Envita's renowned team of dedicated specialists assessed the foremost of these studies and focused on the strengths and inconsistencies of each. Their intense research established a protocol that incorporates only the prime procedures for the expansion and application of cells as a powerful immunotherapy. Our protocols are based on the most recent published research in the field, from a plethora of the most prestigious hospitals and universities, both national and global.

=> The Cells in Your Body that Cancer Fears, Critical to Stage 4 Cancer patients

It is decidedly common knowledge among scientists and physicians that three types of white blood cells can be activated by the immune system to kill cancer cells: cytotoxic T lymphocytes (CTLs), natural killer cells (NKs), and natural killer T cells (NKTs). These cells can be found circulating in the body in low amounts; however, they are clearly a major first-line immune system cancer defense

=> NKs for Stage 4 Breast Cancer Patients

Over the past 20 years, scientific studies have repeatedly documented that breast cancer patients have significantly lower levels of natural killer cells than healthy individuals.1-3 Additionally, NK and NKT function is observably lower in those stricken with breast cancer, indicating severe impairment of the the immune system.2-5

Research findings also relate that progression of disease in these particular patients is associated with decreasing NK activity, and that individuals with a significant family history of breast cancer had lower NK cell activity than people with minor family history of breast cancer.4,6 This basically suggests that defects in NK activity itself may actually contribute to the onset of breast cancer.6 It is noted, without appreciable surprise, that breast cancer patients typically have low levels of interferon-gamma, a major growth factor for NK cells that is naturally produced by the body.3

=> Stage 4 Cancer and Stage 4 Breast Cancer Patients Find NKs are Key

Despite the impairments in NK and NKT cell number and function seen in cancer patients, these cells have been successfully harvested in patients via advanced laboratory techniques - providing the necessary cellular resources for effective immunotherapy.3,5 Published research from Stanford University, the Mayo Clinic, and Harvard University has recently illustrated and supported the importance of natural killer cells and natural killer T cells in patients afflicted with cancer.

In fact, adoptive immunotherapy composed of NK cell infusions has the capacity to instigate clinical regressions in patients with non-Hodgkin's lymphoma, Hodgkin's disease, and leukemia. Moreover, NK cells and cytotoxic T lymphocytes have also been utilized in breast cancer patients with clinical successes noted.7,8 In patients with metastatic breast cancer, NK infusion was well-tolerated and resulted in complete response in 20% of patients.7 In 6 out of 16 patients infused with activated T lymphocytes, objective tumor regressions were observed.8 In animal models of breast cancer, the anti-tumor effects of agents such as interleukin-2 and interleukin-12 were determined to be dependent on NK cells.9,10 Additionally, the presence of activated NK cells and other tumor-fighting immune cells have proven to be major factors in the response of cancer patients to drugs including thaliodomide, Gleevec, and paclitaxel.11-13

=> Envita Immunotherapy - Giving Stage 4 Breast Cancer the "One-Two" Punch

Envita Natural Medical Center is currently utilizing NK cells and CTLs as supportive immunotherapy for cancer patients. Envita's proprietary immune therapy vaccine is referenced as AAIT (for autologous adoptive immune therapy,) and there are 4 major cell types involved - the overall majority being natural killer cells and T cells. The types of cells that make up Envita's treatment are hence listed below:

=> � Natural killer cells=> � Natural killer T cells=> � Cytokine-induced killer cells=> � Cytotoxic T lymphocytes

The vaccine(s) is compiled by expanding a patient's own antitumor immune cells into the billions. These cells are then analyzed for activation markers and tested for their ability to eradicate cancer cells in the laboratory, then subsequently re-infused into the patient.

Enhancement of the immune system is a major benefit in the stampede against cancer, but this vaccine-driven routine may be added upon through subtraction. Simply stated, we can indeed improve results by not only bolstering critical components of the immune system, but simultaneously depleting it of negative factors that impede its functionality.It is common knowledge that cancer cells effect the release of T-regulatory cells, or "negative T cells." The numbers of these cells correlate directly with specific cancer stages - respective to each cancer type. The more advanced the cancer, the higher the T-regulatory cells.

Naturally, through intervention and acting to deplete these cells, along with other key enzymes that block critical immune system, cancer cell-killing action will be accelerated exponentially. Imagine one's immune system being targeted and at the ready, yet something in the body suddenly applies the brakes. This is precisely what most advanced cancer patients are confronted with, regarding high regulatory T cells. Envita's treatment protocols create a targeted vaccine by incorporating the body's most powerful cancer killers, but also depletes the portion of the immune system that inhibits the body from functioning efficiently. Be advised, there is no treatment (conventional or alternative) that can be effective in the later stages of cancer if these negative T-cells are not effectively down-regulated.

Unlike other immunotherapies found in the published literature, Envita's AAIT can be used as a solo treatment. AAIT can also be administered in conjunction with additional therapies that will serve to enhance the effects of cells once they are in the patient. This is a key improvement over many of the studies in the published scientific literature. Envita's AAIT therapy is not just focused on expansion of cells in the laboratory; the ultimate goal is to also keep them activated after they are infused back into the body.

=> Envita Mexico has AAIT Ready and Waiting

The activated natural killer cells in Envita's AAIT are considerably more effective in the realm of tumor obliteration than other similar treatments offered either in Mexico or worldwide. Evidenced by scientific research and clinical results, Envita's AAIT offers a powerful option for those stage 4 breast cancer patients, who are aiming to wage war against cancer while keeping their immune system intact. If you have queries concerning Envita's AAIT, please consult with our team of physicians and patient educators. This particular therapy is offered in Envita Mexico's international cancer center.

=> References

1)Balch CM, Tilden AB, Dougherty PA, Cloud GA. Depressed levels of granular lymphocytes with natural killer (NK) cell function in 247 cancer patients. Ann Surg. 1983 Aug;198(2):192-9.

2)Konjevic G, Spuzic I. Evaluation of different effects of sera of breast cancer patients on the activity of natural killer cells. J Clin Lab Immunol. 1992;38(2):83-93.

3)Caras I, Grigorescu A, Stavaru C, Radu DL, Mogos I, Szegli G, Salageanu A. Evidence for immune defects in breast and lung cancer patients. Cancer Immunol Immunother. 2004 Dec;53(12):1146-52.

4)Garner WL, Minton JP, James AG, Hoffmann CC. Human breast cancer and impaired NK cell function. J Surg Oncol. 1983 Sep;24(1):64-6.

5)Crough T, Purdie DM, Okai M, Maksoud A, Nieda M, Nicol AJ. Modulation of human Valpha24(+)Vbeta11(+) NKT cells by age, malignancy and conventional anticancer therapies. Br J Cancer. 2004 Nov 29;91(11):1880-6.

6)Strayer DR, Carter WA, Brodsky I. Familial occurrence of breast cancer is associated with reduced natural killer cytotoxicity. Breast Cancer Res Treat. 1986;7(3):187-92.

7)deMagalhaes-Silverman M, Donnenberg A, Lembersky B, Elder E, Lister J, Rybka W, Whiteside T, Ball E. Posttransplant adoptive immunotherapy with activated natural killer cells in patients with metastatic breast cancer. J Immunother. 2000 Jan;23(1):154-60.

8)Bishop MR, Fowler DH, Marchigiani D, Castro K, Kasten-Sportes C, Steinberg SM, Gea-Banacloche JC, Dean R, Chow CK, Carter C, Read EJ, Leitman S, Gress R. Allogeneic lymphocytes induce tumor regression of advanced metastatic breast cancer. J Clin Oncol. 2004 Oct 1;22(19):3886-92.

9)Divino CM, Chen SH, Yang W, Thung S, Brower ST, Woo SL. Anti-tumor immunity induced by interleukin-12 gene therapy in a metastatic model of breast cancer is mediated by natural killer cells. Breast Cancer Res Treat. 2000 Mar;60(2):129-34.

10)Joshi SS, Tarantolo SR, Kuszynski CA, Kessinger A. Antitumor therapeutic potential of activated human umbilical cord blood cells against leukemia and breast cancer. Clin Cancer Res. 2000 Nov;6(11):4351-8.

11)Hayashi T, Hideshima T, Akiyama M, Podar K, Yasui H, Raje N, Kumar S, Chauhan D, Treon SP, Richardson P, Anderson KC. Molecular mechanisms whereby immunomodulatory drugs activate natural killer cells: clinical application. Br J Haematol. 2005 Jan;128(2):192-203.

12)Borg C, Terme M, Taieb J, Menard C, Flament C, Robert C, Maruyama K, Wakasugi H, Angevin E, Thielemans K, Le Cesne A, Chung-Scott V, Lazar V, Tchou I, Crepineau F, Lemoine F, Bernard J, Fletcher JA, Turhan A, Blay JY, Spatz A, Emile JF, Heinrich MC, Mecheri S, Tursz T, Zitvogel L. Novel mode of action of c-kit tyrosine kinase inhibitors leading to NK cell-dependent antitumor effects. J Clin Invest. 2004 Aug;114(3):379-88.

13)Kubo M, Morisaki T, Matsumoto K, Tasaki A, Yamanaka N, Nakashima H, Kuroki H, Nakamura K, Nakamura M, Katano M. Paclitaxel probably enhances cytotoxicity of natural killer cells against breast carcinoma cells by increasing perforin production. Cancer Immunol Immunother. 2005 May;54(5):468-76. Epub 2004 Dec 9.

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